MAGNETIC HEATING OF Fe3O4 NANOPARTICLES AND MAGNETIC MICELLES FOR A MAGNETOTHERMALLY-TRIGGERED DRUG DELIVERY SYSTEM FOR CANCER THERAPY by JAMES BRANDON BENNETT CHRISTOPHER S. BRAZEL, CHAIR
نویسندگان
چکیده
منابع مشابه
Magnetothermally responsive star-block copolymeric micelles for controlled drug delivery and enhanced thermo-chemotherapy.
Magnetothermally responsive drug-loaded micelles were designed and prepared for cancer therapy. These specially designed micelles are composed of the thermo-responsive star-block copolymer poly(ε-caprolactone)-block-poly(2-(2-methoxyethoxy)ethyl methacrylate-co-oligo(ethylene glycol)methacrylate) and Mn, Zn doped ferrite magnetic nanoparticles (MZF-MNPs). The thermo-responses of 6sPCL-b-P(MEO2M...
متن کاملPoly (methacrylic acid-co-acrylic acid)-grafted polyvinylpyrrolidone coated Magnetic nanoparticles as a pH-responsive magnetic Nano-carrier for controlled delivery of antibiotics
Objective(s): Pharmaceutical industries are leading to improved medications that can target diseases more effectively and precisely. Researchers have intended to reformulate drugs so that they may be more safely used in human body. The more targeted a drug is, the lower its chance of triggering drug resistance, a cautionary concern surrounding the use of broad-spectrum antibiotics. The aim of t...
متن کاملSynthesis and Characterization of Multifunctional Chitosan-MnFe2O4 Nanoparticles for Magnetic Hyperthermia and Drug Delivery
Multifunctional nanoparticles composed of MnFe₂O₄ were encapsulated in chitosan for investigation of system to combine magnetically-triggered drug delivery and localized hyperthermia for cancer treatment with the previously published capacity of MnFe₂O₄ to be used as an efficient MRI contrast agent for cancer diagnosis. This paper focuses on the synthesis and characterization of magnetic MnFe₂O...
متن کاملCovalent bridging of surface functionalized Fe3O4 and YPO4:Eu nanostructures for simultaneous imaging and therapy.
Magnetic luminescent hybrid nanostructures (MLHN) have received a great deal of attention due to their potential biomedical applications such as thermal therapy, magnetic resonance imaging, drug delivery and intracellular imaging. We report the development of bifunctional Fe3O4 decorated YPO4:Eu hybrid nanostructures by covalent bridging of carboxyl PEGylated Fe3O4 and amine functionalized YPO4...
متن کاملEffects of Ultrasound Irradiation on the Release Profile of 5-fluorouracil from Magnetic Polylactic co-glycolic Acid Nanocapsules
Background: Drug nano-carriers are one of the most important tools for targeted cancer therapy so that undesired side effects of chemotherapy drugs are minimized. In this area, the use of ultrasound can be helpful in controlling drug release from nanoparticles to achieve higher treatment efficiency.Objective: Here, we studies the effects of ultrasound irradiation on the release profile of 5-flu...
متن کامل